Portsmouth got back to winning ways last time out with an impressive 1-0 victory at promotion-chasing Middlesbrough.
A victory over another promotion hopeful in Ipswich on Tuesday (20:00 BST) would put four points of daylight between them and Oxford United in 22nd.
At the top end of the table, Ipswich Town will look to extend their unbeaten run to 10 games, having not lost since a 5-3 defeat by Wrexham in February.
A win would put the Tractor Boys five points clear of third-placed Millwall with a game in hand.
Portsmouth are winless in each of their last nine midweek Championship games (D3 L6), since beating Cardiff City 2-1 in February 2025. Pompey have failed to score in four of their last five midweek games.