The Netherlands international replaces Joe Gomez at Molineux in the only adjustment to the side that started against West Ham United on Saturday.
Liverpool: Alisson, Van Dijk, Konate, Kerkez, Szoboszlai, Mac Allister, Salah, Gakpo, Ekitike, Frimpong, Gravenberch.
Subs: Mamardashvili, Gomez, Chiesa, Jones, Robertson, Nyoni, Ramsay, Morrison, Ngumoha.